Inhibiting HIV by HIV-1 Protease-activated Maize Ribosome-inactivating Protein and the Procedure of Generating the Protein
Invention Reference: 09/MED/331
For a drug to eliminate HIV-infected cells, a major challenge is to achieve high specificity toward target cells but low cytotoxicity toward normal cells. Maize ribosome-inactivating protein (RIP) contains a 25-amino acid internal inactivation region. Removal of this region generates the active...
Inventor(s): Pang Chui Shaw, Yong Tang Zheng, Kam bo Wong, Ka Yee Law, Rui Rui Wang, Nga Sze Mak
Keywords(s):
Category(s): Therapeutics
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