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Compounds Targeting on ABC Transporter-mediated Multidrug Resistance from TCM
Invention Reference: 11/MED/424
The ability of cancer cells to acquire resistance to multiple drugs, termed multidrug resistance (MDR), is often mediated by overexpression of ATP-binding cassette (ABC) transporters that remove substrates out of the cell against a concentration gradient. Among 48 human ABC transporters discovered, three, namely P-glycoprotein...
Inventor(s): Ge Lin, Kin Wah Kenneth To, Stella Chai, Yang Ye, Liang Ma, Chun Ping Tang
Keywords(s):
Category(s): Therapeutics
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