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Epididymis-specific Defensins-based Methods for Evaluating and Affecting Male Fertility
Invention Reference: 04/MED/168
The present invention relates to the discovery that epididymis-specific defensins play an important role in regulating sperm motility and therefore male fertility. Provided are methods for evaluating male fertility based on the level of epididymis-specific defensin(s) bound to sperm, kits for evaluating male fertility,...
Inventor(s): Hsiao Chang Chan, Chenxi Zhou, Chuen Pei Ng, Yiu wa Chung
Keywords(s):
Category(s): Diagnostics, Biotechnology
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Methods for Contraception and Anti-inflammation
Invention Reference: 11/MED/451
We demonstrated that the activation of an epithelial ion channel can trigger signaling cascade leading to the release of PGE2, an important mediator of implantation and inflammation, and upregulation of cyclooxygenase 2 (COX-2), the enzyme important for prostaglandin (PG) production. Interfering with the ion channel...
Inventor(s): Hsiao Chang Chan, Xiao Hua Jiang, Yiu wa Chung
Keywords(s):
Category(s): Therapeutics
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